High Protein Chicken Alfredo Lasagna

You only need a handful of ingredients to make this high protein lasagna. Thanks to frozen lightly breaded chicken breast and a blended cottage cheese alfredo sauce, every layer of lasagna delivers big chicken alfredo flavors with a big dose of protein. One serving has 43g of protein with just 31g of carbs and 500 calories.

Ingredients for Chicken Alfredo Lasagna

I’ll quickly run you through the key components and a few potential swaps or customizations. If you’re in a hurry, there is a full recipe card at the bottom of the post.

The Cottage Cheese Alfredo

I developed this recipe fresh off the heels of another protein packed lasagna with rotisserie chicken that calls for blending low fat cottage cheese with a jar of pasta sauce. It’s such a convenient method for making a lasagna sauce that I went back to the well, combining cottage cheese with a bit of jarred alfredo sauce.

Why reinvent the wheel?

You still get the classic alfredo sauce flavor, but the calories are spread more evenly across an entire lasagna. And since this lasagna incorporates fresh mozzarella and grated parmesan into every layer.

The Crispy Chicken

I used a favorite ingredient of mine in frozen lightly breaded chicken breast bites. I’ve used these bites to make everything from a chicken parm sandwich and pesto chicken pasta to honey chipotle tacos.

As long as it’s lightly breaded, any type of frozen chicken breast bite, tender, nugget, or filet works in this kinda healthy lasagna.

Non-frozen and non-breaded forms of cooked chicken are also options. The rotisserie chicken from my other lasagna comes to mind as another convenient option. Or something like a chicken bolognese would work nicely with the alfredo sauce.

Using non-breaded chicken is a good option for reducing the fat content as well. If you’re on a low fat diet or have limited calories, I would explore using grilled or cooked and chopped chicken breast to save 5+ grams of fat per serving.

Additional Recipe Notes

In addition to the cottage cheese alfredo and crispy chicken, there’s another key difference between this lasagna and my rotisserie chicken lasagna. And that’s the baking dish.

I used a 10.5″x7.5″ baking dish instead of a 13″x9″ to create a taller lasagna with fewer lasagna sheets. Any size baking dish should work, but you may consider doubling the recipe for a larger dish. That way it’s not too thin (and sad).

The finished product is a surprisingly rich lasagna that benefits from brightening with fresh herbs like parsley and basil. Get the herbs on while the lasagna is fresh out of the oven to wake them up.

I would also recommend pairing the lasagna with a green salad with some type of vinaigrette to add more volume to the meal. Something like this with tomatoes, pepperoncini, and red onion would be great.

That’s everything I think you need to know about making a high protein chicken alfredo lasagna. I hope you dig it. If you do, I always appreciate recipe reviews! And if you’re a fan of recipes with cottage cheese, be sure to check out my protein mac and cheese or beefy queso before you head out.